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NIPER JEE 2025 Syllabus: Detailed Subject-Wise Topics & Exam Pattern

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Updated on Feb 13, 2025

Amisha Yadav

NIPER JEE 2025 Syllabus: Detailed Subject-Wise Topics & Exam Pattern

NIPER JEE 2025 Syllabus Overview

The NIPER JEE 2025 exam is administered online via computer-based testing (CBT). The main parts of the exam are as follows:

  • Total Questions: 200 multiple-choice questions (MCQs).
  • Duration: two hours.
  • Marking Scheme: +1 mark for each correct answer; -0.25 for each erroneous response.
  • Sections: Includes subjects such as pharmaceutical sciences, chemistry, biology, mathematics, and general aptitude.
Parameters Details
Total no of questions 200
Total marks in the exam 200 in each paper
Mark for one correct answer 0.5
Mark for one incorrect answer 0.125
Negative marking scheme Yes, applicable

NIPER JEE 2025 Syllabus

Candidates can consult the detailed syllabus in the table below:

Subject Topics
Natural Products Secondary metabolites Phytochemistry Methods of extraction, isolation, and characterization of natural products Biosynthetic pathways Important therapeutic classes Primary metabolites Marine natural products Plant growth regulators Spectroscopy Dietary antioxidants
Stereochemistry Pharmacology and toxicology Evaluation of formulation, principles, and methods of release control in oral formulations Bioavailability, bioequivalence studies Compartmental modelling Packaging Dosage forms Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities (TDDS)  Fischer, sawhorse and Newman projection formulas  Standardization of natural products  Various adrenergic, cholinergic and other receptors  Pharmaceutics and formulation (Pharmaceutical Technology)  Pharmacokinetics  Pharmacodynamics  The pharmacological effect, desired, undesired, toxic, adverse effects  Bioavailability, bioequivalence, various factors of ADME  Drug metabolism  Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways  Pharmacological screening  Mechanism of drug action  Drug-receptor interaction  Detailed study of CNS pharmacology Transdermal drug delivery systems  Diseases  Chemotherapy and pathophysiology  Bioassay methods  Drug delivery systems (DDS)  Carriers in DDS  Biological sources of important classes of natural products  Parenteral  Drug targeting Complexation Solubilisation Dosage form development- stages, implications of dosage form Viscosity measurements
Pharmaceutical analysis Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf-life determination, thermal stability, formulation stability Various analytical techniques Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests. Solubility Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS. Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc.  Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns Osmolality, osmolality, osmotic pressure, conductivity, Preservatives, Media for bioassay. Spectroscopic methods Electrophoresis UV-Visible NMR XRD IR Fluorimetry  HPLC  IR  GC  LCMS  Mass  NMR Peaks  Particle sizing  Chromatography- detailed QA and QC: GLP, TQM, ISO system  Preformulation, cyclodextrin inclusion compounds  Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.  Dosage forms, Stages of dosage form development
Biotechnology and biochemistry Pharmaceutical technology Classification of enzymes and the mechanism of their function of action of  Genetic Engineering  Blotting techniques(Western, southern)  Gel electrophoresis  Gene cloning  Immunoassays, protein  RNA synthesis  DNA synthesis  rDNA technology
Gene expression Mutation Replication Transcription, translation Recombination, bacteriophages
Cloning Fermentation Methods, isolation of nucleic acids, enzymes in cloning
Chemistry Basic organic chemistry and biochemistry Stereochemistry Osazone test Mutarotation Medicinal chemistry and Bulk Drugs Keto-enol tautomerism IUPAC nomenclature Introduction to thermal methods of analysis Introduction to Redox reactions Imine-enamine Hybridization Amino acids proteins Type of stereoisomer Basic methods of synthesis of various organic compounds Named reactions Various Heterocycles, Heterocycle synthesis, reactions Tautomerism Spectroscopy Resolution methods Reaction kinetics, first second third and pseudo-first-order reactions, radiolabeling for determination of mechanism. Racemic mixture R and S nomenclature Reactions like Cannizarro’s reaction Pericyclic reactions Ester hydrolysis Huckel’s rule reaction mechanisms- E and Z isomerism Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen Chromatography Carbohydrates classification Aromaticity
Aptitude Simple Mathematics logical reasoning and data analysis, questions based on the English language
Pharmacology Bioavailability, bioequivalence, various factors of ADME Bioassay methods, various requirements. Brief knowledge of the statistical tests. Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases. Diseases: a study of the pharmacology of the diseases and drugs used with the mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodulation. Study of the basis of threshold areas of work in NIPER in the pharmacology dept. Mentioned in the brochure. Detailed study of CNS pharmacology especially opioid receptors Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects. Drug metabolism: various pathways and other details. Drug interactions, agonist, antagonist, Mechanism of drug action, drug-receptor interaction. Various adrenergic, cholinergic and other receptors Partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.
Phytochemistry Methods of extraction, isolation, and characterization of natural products. Various separation techniques used for the isolation of natural products. Biosynthetic pathways. Primary metabolites, their examples Secondary metabolites, various classes of secondary metabolites (Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, etc.). Important therapeutic classes: anti-diabetics, hepato-protectives, immunomodulators, nutraceuticals, natural products for gynaecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc. Dietary antioxidants, Marine natural products, plant growth regulators. Fischer projection formulas. Biological sources of important classes of natural products. (Selected ones only) Standardization of natural products, analytical pharmacognosy. Difference between natural products and pharmacognosy Some knowledge about types and preparation of ayurvedic formulations like asava, arista etc.

NIPER JEE 2025 Syllabus Changes

For NIPER JEE 2025, the syllabus remains largely similar to previous years. However, candidates should check for any minor changes announced by NIPER.

NIPER JEE 2025 Syllabus Important Books & Resources

Pharmaceutical Sciences

  • The Theory and Practice of Industrial Pharmacy – Leon Lachman
  • Remington: The Science and Practice of Pharmacy – Joseph Remington

Chemistry

  • Organic Chemistry – Morrison and Boyd
  • Inorganic Chemistry – J.D. Lee

Biology

  • Molecular Biology of the Cell – Alberts
  • Genetics: A Conceptual Approach – Benjamin Pierce

Mathematics & General Aptitude

  • R.S. Aggarwal – Quantitative Aptitude
  • Arun Sharma – Logical Reasoning

NIPER JEE 2025 Syllabus: Preparation Tip by Subject

  • Prioritise high-impact topics such as pharmacology and medicinal chemistry.
  • Chemistry: Concentrate on organic and physical chemistry fundamentals.
  • Biology: Improve molecular biology and genetics.
  • Mathematics: Practice common test topics such as algebra and probability.
  • General Aptitude: Use prior year's problems to strengthen your reasoning skills.

NIPER JEE 2025 Syllabus: Sample and Previous Year Papers

Practice past NIPER JEE 2025 curriculum papers is crucial. Candidates can get sample papers on:

  • Official NIPER webpage.
  • Coaching institute portals
  • Reference books include solved papers.

NIPER JEE 2025 Syllabus: Common Mistakes To Avoid

  • Ignoring high-weightage subjects: Pharmaceutical sciences should be the primary focus.
  • Lack of revision: Regular revision is required to maintain concepts.
  • Skipping sample papers: Mock tests help with time management.
  • Overlooking General Aptitude: With proper preparation, this portion might yield easy marks.

NIPER JEE 2025 Syllabus FAQs

What is the official NIPER JEE 2025 syllabus?

The NIPER JEE 2025 syllabus includes subjects like Pharmaceutical Sciences, Chemistry, Biology, Mathematics, and General Aptitude.

Has the NIPER JEE 2025 syllabus changed from previous years?

There are no major changes in the NIPER JEE 2025 syllabus, but candidates should check official updates.

Which subject has the highest weightage in the NIPER JEE 2025 syllabus?

Pharmaceutical Sciences carries the highest weightage in the NIPER JEE 2025 syllabus.

Where can candidates download the NIPER JEE 2025 syllabus PDF?

The official NIPER JEE 2025 syllabus PDF is available on the NIPER website.

What are the most important topics in the NIPER JEE 2025 syllabus?

Topics like Pharmacology, Medicinal Chemistry, and Organic Chemistry are crucial.

How should candidates prepare for the NIPER JEE 2025 syllabus?

Focus on high-weightage topics and solve previous year papers for better understanding.

What is the role of General Aptitude in the NIPER JEE 2025 syllabus?

General Aptitude holds 5-10% weightage but can help boost the overall score.

Is mathematics mandatory in the NIPER JEE 2025 syllabus?

Yes, Mathematics is a part of the NIPER JEE 2025 syllabus, covering Algebra and Calculus.

Are NCERT books sufficient for the NIPER JEE 2025 syllabus?

NCERT books are helpful but should be supplemented with advanced reference books.

How many months are required to complete the NIPER JEE 2025 syllabus?

A well-planned 3-6 months of preparation is recommended for the NIPER JEE 2025 syllabus.

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